abstract：OBJECTIVE:To assess the effect of race on the incidence of aortic stenosis (AS) and utilization and outcomes of aortic valve replacement (AVR). PATIENTS AND METHODS:Patients older than 60 years hospitalized with a primary diagnosis of AS and those who underwent AVR between 2003 and 2014 were included. Adjusted and una...

journal_title：Mayo Clinic proceedings

authors： Alqahtani F,Aljohani S,Amin AH,Al-Hijji M,Ali OO,Holmes DR,Alkhouli M

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:Given that patients with non-dialysis-dependent chronic kidney disease (NDD-CKD) have a disproportionately higher prevalence of hypothyroidism compared with their non-CKD counterparts, we sought to determine the association between thyroid status, defined by serum thyrotropin (TSH) levels, and mortality among...

journal_title：Mayo Clinic proceedings

authors： Rhee CM,Kalantar-Zadeh K,Ravel V,Streja E,You AS,Brunelli SM,Nguyen DV,Brent GA,Kovesdy CP

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:To assess whether dietary supplements that are herbal and/or animal-derived products, marketed for enhancing metabolism or promoting energy, "adrenal fatigue," or "adrenal support," contain thyroid or steroid hormones. METHODS:Twelve dietary adrenal support supplements were purchased. Pregnenolone, androsten...

journal_title：Mayo Clinic proceedings

authors： Akturk HK,Chindris AM,Hines JM,Singh RJ,Bernet VJ

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:To present a multiyear clinical experience with intravenous bevacizumab for the management of severe gastrointestinal bleeding and/or epistaxis in patients with hereditary hemorrhagic telangiectasia (HHT). PATIENTS AND METHODS:All patients treated with intravenous bevacizumab for severe hereditary hemorrhagi...

journal_title：Mayo Clinic proceedings

authors： Iyer VN,Apala DR,Pannu BS,Kotecha A,Brinjikji W,Leise MD,Kamath PS,Misra S,Begna KH,Cartin-Ceba R,DuBrock HM,Krowka MJ,O'Brien EK,Pruthi RK,Schroeder DR,Swanson KL

更新日期：2018-02-01 00:00:00

abstract：:There is an ongoing debate in the medical community regarding the effects of testosterone on cardiovascular (CV) health. For decades, there has been conflicting evidence regarding the association of endogenous testosterone levels and CV disease (CVD) events that has resulted in much debate and confusion among health c...

journal_title：Mayo Clinic proceedings

authors： Elagizi A,Köhler TS,Lavie CJ

更新日期：2018-01-01 00:00:00

abstract：:Genitourinary syndrome of menopause (GSM), previously known as atrophic vaginitis or vulvovaginal atrophy, affects more than half of postmenopausal women. Caused by low estrogen levels after menopause, it results in bothersome symptoms, including vaginal dryness, itching, dyspareunia, urinary urgency and increased fre...

journal_title：Mayo Clinic proceedings

authors： Faubion SS,Sood R,Kapoor E

更新日期：2017-12-01 00:00:00

abstract：:Clinical guidelines for instituting pharmacotherapy for the primary prevention of atherosclerotic cardiovascular disease (ASCVD), specifically lipid management and aspirin, have long been based on absolute risk. However, lipid management in the current era remains challenging to both patients and clinicians in the set...

journal_title：Mayo Clinic proceedings

authors： Michos ED,Blaha MJ,Blumenthal RS

更新日期：2017-12-01 00:00:00

abstract：:Rapid eye movement sleep behavior disorder (RBD) is diagnosed by a clinical history of dream enactment accompanied by polysomnographic rapid eye movement sleep atonia loss (rapid eye movement sleep without atonia). Rapid eye movement sleep behavior disorder is strongly associated with neurodegenerative disease, especi...

journal_title：Mayo Clinic proceedings

authors： St Louis EK,Boeve BF

更新日期：2017-11-01 00:00:00

abstract：:Recognizing the contribution art has had in the Mayo Clinic environment since the original Mayo Clinic Building was finished in 1914, Mayo Clinic Proceedings features some of the numerous works of art displayed throughout the buildings and grounds on Mayo Clinic campuses as interpreted by the author. ...

journal_title：Mayo Clinic proceedings

authors： Wentz MR

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:In essential tremor and Parkinson disease (PD) tremor, administration of onabotulinumtoxinA via a fixed injection approach improves the tremor, but many patients (30%-70%) develop moderate to severe hand weakness, limiting the use of onabotulinumtoxinA in clinical practice. OBJECTIVE:To evaluate the safety ...

journal_title：Mayo Clinic proceedings

authors： Mittal SO,Machado D,Richardson D,Dubey D,Jabbari B

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:To measure carotid artery intima-media thickness (CIMT), a marker of subclinical atherosclerosis, in postmenopausal women with and without histories of preeclampsia and to synthesize these results with those from prior studies of CIMT performed 10 or more years after preeclamptic pregnancies. PATIENTS AND ME...

journal_title：Mayo Clinic proceedings

authors： Garovic VD,Milic NM,Weissgerber TL,Mielke MM,Bailey KR,Lahr B,Jayachandran M,White WM,Hodis HN,Miller VM

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVE:To assess whether caffeine intake is associated with all-cause and cause-specific mortality. PATIENTS AND METHODS:We conducted a prospective cohort study using data from the National Health and Nutrition Examination Survey 1999-2010. Cox proportional hazards models were used to compare the multivariate-adjus...

journal_title：Mayo Clinic proceedings

authors： Tsujimoto T,Kajio H,Sugiyama T

更新日期：2017-08-01 00:00:00

abstract：:The updated cervical cancer screening guidelines recommend that women at average risk who have negative screening results undergo cervical cytological testing every 3 to 5 years. These recommendations do not pertain to women at high risk for cervical cancer. This article reviews recommendations for cervical cancer scr...

journal_title：Mayo Clinic proceedings

authors： Vegunta S,Files JA,Wasson MN

更新日期：2017-08-01 00:00:00

abstract：:After the completion of the Human Genome Project, there has been an acceleration in methodologies on sequencing nucleic acids (DNA and RNA) at a high precision and with ever-decreasing turnaround time and cost. Collectively, these approaches are termed next-generation sequencing and are already affecting the transform...

journal_title：Mayo Clinic proceedings

authors： Stephens MC,Boardman LA,Lazaridis KN

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:To examine the association between specific adipose tissue depots and the risk of incident cancer in the Dallas Heart Study. PATIENTS AND METHODS:Individuals without prevalent cancer in the Dallas Heart Study underwent quantification of adipose depots: visceral adipose tissue (VAT), abdominal subcutaneous ad...

journal_title：Mayo Clinic proceedings

authors： Gupta A,Pandey A,Ayers C,Beg MS,Lakoski SG,Vega GL,Grundy SM,Johnson DH,Neeland IJ

更新日期：2017-04-01 00:00:00

abstract：:Cardiac rehabilitation (CR) services improve various clinical outcomes in patients with cardiovascular disease, but such services are underutilized, particularly in women. The aim of this study was to identify evidence-based barriers and solutions for CR participation in women. A literature search was carried out usin...

journal_title：Mayo Clinic proceedings

authors： Supervía M,Medina-Inojosa JR,Yeung C,Lopez-Jimenez F,Squires RW,Pérez-Terzic CM,Brewer LC,Leth SE,Thomas RJ

更新日期：2017-03-13 00:00:00

abstract：:Mature women often present with symptomatic vulvovaginal atrophy and vulvar dermatoses, causing noncoital pain, dyspareunia, and sexual changes. Diagnosis of these conditions can be challenging, and long-term management is required to decrease morbidity and enhance quality of life. Vaginal estrogen therapies remain sa...

journal_title：Mayo Clinic proceedings

authors： Marnach ML,Torgerson RR

更新日期：2017-03-01 00:00:00

abstract：:There is overwhelming evidence that racial and ethnic minorities face multiple health care disparities. Recognizing and addressing cultural and religious/spiritual (RS) values is a critical aspect of providing goal-concordant care for patients facing a serious illness, especially at the end of life. Failure to address...

journal_title：Mayo Clinic proceedings

authors： Partain DK,Ingram C,Strand JJ

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To describe the Mayo Clinic experience with emergency video telemedicine consultations for high-risk newborn deliveries. PATIENTS AND METHODS:From March 26, 2013, through December 31, 2015, the Division of Neonatal Medicine offered newborn telemedicine consultations to 6 health system sites. A wireless table...

journal_title：Mayo Clinic proceedings

authors： Fang JL,Collura CA,Johnson RV,Asay GF,Carey WA,Derleth DP,Lang TR,Kreofsky BL,Colby CE

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:To investigate the association between physical activity (PA) and risk of mortality in a large middle-aged cohort stratified by inflammatory status. PATIENTS AND METHODS:A total of 336,560 individuals (mean age, 39.7 years; 58% male) who underwent comprehensive health screenings were enrolled in this prospec...

journal_title：Mayo Clinic proceedings

authors： Lee JY,Ryu S,Cheong E,Sung KC

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:To estimate the age- and sex-adjusted incidence of melanoma in adults 61 years or older in Olmsted County, Minnesota, from 1970 through 2009. PATIENTS AND METHODS:Using Rochester Epidemiology Project resources, 397 patients were identified who were 61 years or older and who received a first lifetime diagnosi...

journal_title：Mayo Clinic proceedings

authors： Olazagasti Lourido JM,Ma JE,Lohse CM,Brewer JD

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:To elucidate the long-term clinical behavior, treatment, and outcomes of sporadic facial nerve schwannoma (FNS) in a large cohort of patients managed in the post-magnetic resonance imaging era. PATIENTS AND METHODS:Retrospective review at a single tertiary health care system (January 1, 1990, through Decembe...

journal_title：Mayo Clinic proceedings

authors： Carlson ML,Deep NL,Patel NS,Lundy LB,Tombers NM,Lohse CM,Link MJ,Driscoll CL

更新日期：2016-11-01 00:00:00

abstract：:Sleep disorders and neurodegenerative diseases are commonly encountered in primary care. A common, but underdiagnosed sleep disorder, rapid eye movement sleep behavior disorder (RBD), is highly associated with Parkinson disease and related disorders. Rapid eye movement sleep behavior disorder is common. It is estimate...

journal_title：Mayo Clinic proceedings

authors： McCarter SJ,Howell MJ

更新日期：2016-10-01 00:00:00

abstract：:There are a number of changes underway in modern clinical bacteriology laboratories. Panel-based molecular diagnostics are now available for numerous applications, including, but not limited to, detection of bacteria and select antibacterial resistance markers in positive blood culture bottles, detection of acute gast...

journal_title：Mayo Clinic proceedings

authors： Patel R

更新日期：2016-10-01 00:00:00

abstract：:Gastric and gastroesophageal adenocarcinomas continue to be a major health burden globally and collectively represent the third leading cause of cancer death. Among patients with metastatic disease, most die of their cancer because of the limited number of modestly effective treatment regimens available today. The pro...

journal_title：Mayo Clinic proceedings

authors： Elimova E,Mizrak Kaya D,Harada K,Ajani JA

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:To assess early and late outcomes, including bleeding, in patients with thrombocytopenia undergoing percutaneous coronary intervention (PCI). PATIENTS AND METHODS:We performed a retrospective single-center study of patients with preprocedural thrombocytopenia (platelet count ≤100,000/μL; n=204) undergoing PC...

journal_title：Mayo Clinic proceedings

authors： Raphael CE,Spoon DB,Bell MR,Psaltis PJ,Kidd S,Loh SX,Lennon RJ,Singh M,Rihal C,Gulati R

更新日期：2016-08-01 00:00:00

abstract：:Diverticular disease is a common condition that is associated with variable presentations. For this review article, we performed a review of articles in PubMed through February 1, 2016, by using the following MeSH terms: colon diverticula, colonic diverticulitis, colonic diverticulosis, colonic diverticulum, colonic d...

journal_title：Mayo Clinic proceedings

authors： Feuerstein JD,Falchuk KR

更新日期：2016-08-01 00:00:00

abstract：:In August 2015, an expert colloquium commissioned by the Sexual Medicine Society of North America (SMSNA) convened in Washington, DC, to discuss the common clinical scenario of men who present with low testosterone (T) and associated signs and symptoms accompanied by low or normal gonadotropin levels. This syndrome is...

journal_title：Mayo Clinic proceedings

authors： Khera M,Broderick GA,Carson CC 3rd,Dobs AS,Faraday MM,Goldstein I,Hakim LS,Hellstrom WJ,Kacker R,Köhler TS,Mills JN,Miner M,Sadeghi-Nejad H,Seftel AD,Sharlip ID,Winters SJ,Burnett AL

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:To investigate whether the use of systemic glucocorticoids is a risk factor for community-acquired Staphylococcus aureus bacteremia (CA-SAB). PATIENTS AND METHODS:We used population-based medical registries in Northern Denmark to conduct a case-control study including all adults with first-time CA-SAB and ma...

journal_title：Mayo Clinic proceedings

authors： Smit J,Kaasch AJ,Søgaard M,Thomsen RW,Nielsen H,Frøslev T,Schønheyder HC

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:To assess the association between exercise capacity and the risk of developing atrial fibrillation (AF). PATIENTS AND METHODS:A symptom-limited exercise tolerance test was conducted to assess exercise capacity in 5962 veterans (mean age, 56.8±11.0 years) from the Veterans Affairs Medical Center, Washington, ...

journal_title：Mayo Clinic proceedings

authors： Faselis C,Kokkinos P,Tsimploulis A,Pittaras A,Myers J,Lavie CJ,Kyritsi F,Lovic D,Karasik P,Moore H

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:To estimate the prevalence of healthy lifestyle characteristics and to examine the association between different combinations of healthy lifestyle characteristics and cardiovascular disease biomarkers. PATIENTS AND METHODS:The prevalence of healthy lifestyle characteristics was estimated for the US adult pop...

journal_title：Mayo Clinic proceedings

authors： Loprinzi PD,Branscum A,Hanks J,Smit E

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:To provide external validation of the diagnostic accuracy of the Sleep Apnea Clinical Score (SACS) tool in a new setting and patient population. PATIENTS AND METHODS:We conducted a prospective cohort study. Potential participants were adult family medicine patients. We excluded patients with a SACS of 0, kno...

journal_title：Mayo Clinic proceedings

authors： Grover M,Mookadam M,Chang YH,Parish J

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:To study the relationship between body mass index (BMI) and central obesity and mortality in elderly patients with coronary artery disease (CAD). PATIENTS AND METHODS:We identified 7057 patients 65 years or older from 5 cohort studies assessing mortality risk using either waist circumference (WC) or waist-hi...

journal_title：Mayo Clinic proceedings

authors： Sharma S,Batsis JA,Coutinho T,Somers VK,Hodge DO,Carter RE,Sochor O,Kragelund C,Kanaya AM,Zeller M,Park JS,Køber L,Torp-Pedersen C,Lopez-Jimenez F

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To assess obesity rates during childhood and young adulthood in patients with attention-deficit/hyperactivity disorder (ADHD) and age- and sex-matched controls derived from a population-based birth cohort because cross-sectional studies suggest an association between ADHD and obesity. PATIENTS AND METHODS:St...

journal_title：Mayo Clinic proceedings

authors： Aguirre Castaneda RL,Kumar S,Voigt RG,Leibson CL,Barbaresi WJ,Weaver AL,Killian JM,Katusic SK

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To describe the survival of a large nonobstructive hypertrophic cardiomyopathy (NO-HCM) cohort and to identify risk factors for increased mortality in this population. PATIENTS AND METHODS:Patients were identified from the Mayo Clinic HCM database from January 1, 1975, through November 30, 2006, for this ret...

journal_title：Mayo Clinic proceedings

authors： Hebl VB,Miranda WR,Ong KC,Hodge DO,Bos JM,Gentile F,Klarich KW,Nishimura RA,Ackerman MJ,Gersh BJ,Ommen SR,Geske JB

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To determine the incidence and predictors of infective endocarditis (IE) in a population-based cohort of patients with mitral valve prolapse (MVP). PATIENTS AND METHODS:We identified all adult Olmsted County residents with MVP diagnosed by echocardiography from January 1989 to December 1998 and cross-matched...

journal_title：Mayo Clinic proceedings

authors： Katan O,Michelena HI,Avierinos JF,Mahoney DW,DeSimone DC,Baddour LM,Suri RM,Enriquez-Sarano M

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To examine the effect of objectively measured exercise capacity (EC) on early mortality (EM) after a first myocardial infarction (MI). PATIENTS AND METHODS:This retrospective cohort study included 2061 patients without a history of MI (mean age, 62±12 years; 38% [n=790] women; 56% [n=1153] white) who underwe...

journal_title：Mayo Clinic proceedings

authors： Shaya GE,Al-Mallah MH,Hung RK,Nasir K,Blumenthal RS,Ehrman JK,Keteyian SJ,Brawner CA,Qureshi WT,Blaha MJ

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:To estimate the incidence of selected systemic autoimmune diseases (SAIDs) in approximately 14,000 male rescue/recovery workers enrolled in the Fire Department of the City of New York (FDNY) World Trade Center (WTC) Health Program and to compare FDNY incidence to rates from demographically similar men in the ...

journal_title：Mayo Clinic proceedings

authors： Webber MP,Moir W,Crowson CS,Cohen HW,Zeig-Owens R,Hall CB,Berman J,Qayyum B,Jaber N,Matteson EL,Liu Y,Kelly K,Prezant DJ

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To determine the incidence and distribution of radical prostatectomy (RP) in the United States over time. PATIENTS AND METHODS:We conducted a serial cross-sectional analysis of time trends using the Nationwide Inpatient Sample of adult men older than 45 years who underwent RP between January 1, 1998, and Dec...

journal_title：Mayo Clinic proceedings

authors： Tyson MD 2nd,Andrews PE,Ferrigni RF,Humphreys MR,Parker AS,Castle EP

更新日期：2016-01-01 00:00:00

abstract：:Low back pain (LBP) is a leading cause of disability worldwide. In the absence of a classification system for pain syndromes, classification of LBP on the basis of the distribution of pain as axial (pain generally localized to the low back) or radicular neuropathic (pain radiating to the lower extremities) is relevant...

journal_title：Mayo Clinic proceedings

authors： Hooten WM,Cohen SP

更新日期：2015-12-01 00:00:00